There are a lot of posts out there about how to make your guests feel comfortable.
Here's a confession. This one is kind of bad. . . .
I don't worry too much about making them comfortable. I'll put forth an effort, but not a huge one. I worry more about being inconvenienced. I have a routine and I like it. I also don't much care for change, which is why my living room furniture is still arranged the same way it was when we moved into the house eight years ago.
Here's what I do for guests so that they're comfortable and I'm not inconvenienced.
First, we are lucky enough to have a spare bedroom with its own bath. Someday, when the kids are older and I decide they shouldn't share a bathroom, I will probably move one of them in there. For the time being, neither one can keep a bathroom neat and tidy, and I don't care to have one more mess in the house, so they are sharing. This helps so that I don't have guests wandering the hall at night looking for a place to pee. I'm a light sleeper and this would seriously freak me out.
In an effort to keep the guests from wandering at night, we have a television in the room. They can shut their door, turn on their TV and be entertained. . . and I don't have to participate! There's no awkward "whatever you want to watch" moments and I can go to sleep when I want to, instead of staying up and keeping them company in the living room while they watch David Letterman.
My sister can not see without her glasses. After her first visit with us, she told me that I need to have a place next to the bed for guests to put things like glasses. She used a chair while visiting us and, shortly after, I found this gem at a garage sale. I've been meaning to refinish it (that's solid wood!!!) but I haven't gotten around to it.
One of the "necessities" is a power strip. Everyone has a cell phone that needs charging. Usually they have a laptop or tablet with them. I don't have that many exposed outlets in the room and I used to have guests pulling out the furniture to get to an empty outlet. A power strip fixes this.
I also try to leave room in the closet. The spare bedroom closet stores our off season clothes and, during the summer, has stacks and stacks of the blankets that are on our beds in the wintertime. I always make sure to clear a space, just in case.
I also keep a spare blanket and pillows handy. We keep our house cold in the winter and in the summer, the fans are all on. I actually bring an extra blanket and pillow to homes I stay in because, often, I need an extra pillow and I'm cold. Since it's summer, the spare blankets are stacked in my closet. In the winter, I'd leave one out in plain sight.
That's about it! Like I said, I don't worry too much about making guests comfortable. . . they may want to stay longer! I do love a good visit but I also love the moment after everyone leaves and you can drop the smile, quit planning the next meal, and listen to the quiet.